Detalhe da pesquisa
1.
Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
Proc Natl Acad Sci U S A
; 120(13): e2222073120, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36961924
2.
Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.
Nature
; 568(7752): 415-419, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30971821
3.
Entropic Overcompensation of the N501Y Mutation on SARS-CoV-2 S Binding to ACE2.
J Chem Inf Model
; 63(2): 633-642, 2023 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36584335
4.
Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2.
J Biol Chem
; 297(4): 101151, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478710
5.
Target identification for repurposed drugs active against SARS-CoV-2 via high-throughput inverse docking.
J Comput Aided Mol Des
; 36(1): 25-37, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825285
6.
Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins.
J Virol
; 94(10)2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32161177
7.
Roles of the Coupling Agent and Surfactant in Droplet Structure in Sizing Emulsions: A Molecular Dynamics Simulations Study.
Langmuir
; 37(33): 10183-10190, 2021 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34396774
8.
Atomistic simulation of volumetric properties of epoxy networks: effect of monomer length.
Soft Matter
; 17(43): 9957-9966, 2021 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34698327
9.
Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate.
Biochem J
; 477(21): 4263-4280, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33057580
10.
Metastable HIV-1 Surface Protein Env Sensitizes Cell Membranes to Transformation and Poration by Dual-Acting Virucidal Entry Inhibitors.
Biochemistry
; 59(6): 818-828, 2020 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31942789
11.
A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity.
J Virol
; 93(24)2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31554684
12.
Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 Stereoisomer.
J Virol
; 93(21)2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31391272
13.
Mapping saddles and minima on free energy surfaces using multiple climbing strings.
J Chem Phys
; 151(12): 124112, 2019 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31575198
14.
Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus.
Biochem J
; 475(5): 931-957, 2018 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29343613
15.
Multiscale implementation of infinite-swap replica exchange molecular dynamics.
Proc Natl Acad Sci U S A
; 113(42): 11744-11749, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27698148
16.
Roles of conserved tryptophans in trimerization of HIV-1 membrane-proximal external regions: Implications for virucidal design via alchemical free-energy molecular simulations.
Proteins
; 86(7): 707-711, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29633345
17.
Lipid flip-flop vs. lateral diffusion in the relaxation of hemifusion diaphragms.
Biochim Biophys Acta Biomembr
; 1860(7): 1452-1459, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29684332
18.
Recognition of HIV-inactivating peptide triazoles by the recombinant soluble Env trimer, BG505 SOSIP.664.
Proteins
; 85(5): 843-851, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28056499
19.
Rate of hemifusion diaphragm dissipation and ability to form three-junction bound HD determined by lipid composition.
J Chem Phys
; 147(13): 134903, 2017 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28987088
20.
Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer.
Biochemistry
; 55(44): 6100-6114, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27731975